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AdipoGen E-News | June/July 2012

AdipoGen - A Leading Manufacturer of
New & Unique Interleukin Reagents

Excellent tool to block IL-36 signaling in vivo or in vitro
IL-36Ra [IL-1F5] (mouse) (rec.)
MultiPack. Savings!
  10 µg
3 x 10 µg

Figure:  IL-36Ra (mouse) (rec.) (Prod. No. AG-40B-0096) inhibits IL-36α, IL-36β, IL-36γ-dependent expression of IL-6 in mouse bone marrow-derived dendritic cells (BMDCs).

Method: Bone marrow cells were differentiated into BMDCs using GM-CSF (20ng/ml) for 10 days. BMDCs were cultured with or without IL-36Ra, IL-36α, IL-36β, IL-36γ or LPS at indicated concentrations for 72 h. Cell supernatants were then harvested and IL-6 levels determined by ELISA.



NEW fully characterized IL-36 and IL-36R proteins
IL-36α [IL-1F6] (mouse) (rec.)   AG-40B-0098-C010   10 µg
IL-36β [IL-1F8] (mouse) (rec.)   AG-40B-0099-C010   10 µg
IL-36γ [IL-1F9] (mouse) (rec.)   AG-40B-0100-C010   10 µg
IL-36γ [IL-1F-9] (mouse) (rec.) (FLAG)   AG-40B-0105-C010   10 µg
IL-36Ra (human) (rec.)
MultiPack. Savings!
  10 µg
3 x 10 µg

Other new Interleukin Reagents
IL-1α (mouse), mAb (Bamboo-1)   AG-20B-0050-C100   100 µg
IL-33 (mouse), mAb (rec.) (Carly-1-4)   AG-27B-0012-C100   100 µg
IL-38 [IL-1F10] (mouse) (rec.) (FLAG)   AG-40B-0101-C010   10 µg

Quantitative Measurement

of Inflammasome Activation

NEW Caspase-1 (mouse) Detection Set
Caspase-1 (mouse) Matched Pair
Detection Set

  AG-46B-0003-KI01   1 Set
Figure:  Detection of mouse caspase-1 in cell culture supernatants by ELISA.

Method: Mouse caspase-1 measured by ELISA in supernatants of differentiated bone marrow-derived dendritic cells (BMDCs) from wild-type (WT) or caspase-1-/- (KO) mice activated or not activated by 5 μM Nigericin (Nig) (AG-CN2-0020) for 30 min.

Also available:  
Caspase-1 (p10) (mouse), mAb (Casper-2)
Caspase-1 (p10) (mouse), mAb (Casper-2) (Biotin)
Caspase-1 (p20) (mouse), mAb (Casper-1)
Caspase-1 (p20) (mouse), mAb (Casper-1) (Biotin)
Caspase-1 (p20) (human), mAb (Bally-1)

Newly released at AdipoChem
BQ-123 . sodium salt
Potent and selective endothelin receptor A (ETA) antagonist
  1 mg
5 mg
BULK available!
Potent aldose reductase inhibitor. Antioxidant.
  0.5 mg
1 mg
5 mg
BULK available!
Also newly available:
Atpenin A5 | Citrinin | EM574 [Motilide] | (R,R)-Hymeglusin | Lactacystin | Prodigiosin | Pyripyropene AMalformin C | Rosiglitazone . maleate | Trichostatin A

Ask for discounted BULK quantities!

Visit our Website for a comprehensive overview of all Products.

For Ordering please visit: www.adipogen.com
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