AdipoGen E-News | March 2012
(In Memory of Jürg Tschopp)
NEW: CASPER-1 & CASPER-2
Unique mAbs to detect activated mouse Caspase-1 by WB
- Purified mouse monoclonal antibodies (mAbs)
- CASPER-1 detects endogenous full-length & activated p20 fragment
- CASPER-2 detects endogenous full-length & activated p10 fragment
- Best tools to monitor the inflammasome activation
- Tested and approved by experts in the inflammasome field
Figure: Mouse Caspase-1 (p10) is detected by immunoblotting using anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Prod. No AG-20B-0044).
Method: Caspase-1 was analyzed by Western blot in supernatants of differentiated bone marrow-derived dendritic cells (BMDCs) from wild-type and caspase-1 knockout mice activated or not by 5μM Nigericin for 30min (Prod. No. AG-CN2-0020). Supernatants (30μl) were separated by SDS-PAGE under reducing conditions, transferred to nitrocellulose and incubated with anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (1μg/ml). Proteins were visualized by a chemiluminescence detection system.
Flagellin - The Source!
AdipoGen offers 2 different qualities of Flagellin.
The standard Flagellin with a purity of >90% (SDS-PAGE) and endotoxin content of <0.1EU/µg.
"HighPurity" Flagellin with a purity of >95% (SDS-PAGE) and endotoxin content of <0.01EU/µg.
New Antibodies from the Bench
Powerful Tools for Inflammasome Research
|Nigericin . Na
NLRP3/NALP3 inflammasome activator
Ask for discounted BULK quantities!
Visit our Website for a comprehensive overview of Inflammasome Research Reagents.
One year ago on March 22nd, our dear friend
Jürg Tschopp passed away and left a huge gap.
In memory and to honor his achievements, AdipoGen dedicates him this new Inflamma-