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AdipoGen E-News | June 2011

Notch Ligands - Cancer & Stem Cell Research Tools

The Notch signaling pathway is essential for cell differentiation and cell fate decision. The components have been associated with various disorders such as cancer, leukemia, immune disorders, developmental syndromes, stroke, cognitive symptoms and metabolic disorders.


NEW INSIGHTS:


  • DLL1 is involved in differentiation and self-renewal of adipocyte stem cells.
  • DLK1 is a regulator of adipocyte differentiation. Soluble DLK1 levels affect adipogenesis and control mesenchymal cell fate.
  • Soluble human DLK1 and DLL1 might become biomarkers for metabolic dysfunctions.
DLK1, Soluble (human) ELISA Kit
AG-45A-0032EK-KI01
AG-45A-0032TP-KI01
AG-45A-0032PP-KI01
96 wells
2 x 96 wells
5 x 96 wells
SPECIES REACTIVITY:Human
SENSITIVITY:336 pg/ml
RANGE:0.47 to 30 ng/ml
DETECTION TYPE:Colorimetric
ASSAY TYPE:Sandwich
SAMPLE TYPE:Serum,
Cell Culture Supernatant
Download Manual

DLL1, Soluble (human) ELISA Kit
Potential Biomarker for Metabolic Disorders
  AG-45A-0027EK-KI01
AG-45A-0027TP-KI01
AG-45A-0027PP-KI01
 

96 wells
2 x 96 wells
5 x 96 wells



Not(ch)ust Ordinary Tools from the Bench
anti-DLK1 (human), mAb (PF299-1)
IHC and FACS-competent Antibody
  AG-20A-0070-C050
AG-20A-0070-C100
  50 µg
100 µg
anti-Jagged-1 (human), mAb (J1G53-3)
IHC and FACS-competent Antibody
  AG-20A-0049-C100
 
  100 µg
DLK1 (human):Fc (human) (rec.)
DLK1 (mouse):Fc (human) (rec.)
DLL1 (human):Fc (human) (rec.)
DLL1 (mouse):Fc (human) (rec.)
Jagged-1 (human):Fc (human) (rec.)
Jagged-1 (mouse):Fc (human) (rec.)
DNER (ED) (human):Fc (human) (rec.)
DNER (ED) (mouse):Fc (human) (rec.)
All proteins show Adipogenesis Inhibition!
  AG-40A-0118
AG-40A-0107
AG-40A-0116
AG-40A-0148
AG-40A-0081
AG-40A-0157
AG-40A-0119
AG-40A-0177
  All available as
10 µg and 50 µg

BULK available!
DAPT
Notch processing inhibitor
  AG-CR1-0016-M005
AG-CR1-0016-M025
  5 mg
25 mg
BULK available!
Visit our Website to learn more about our Notch Ligands


NEW from the Bench
Zerumbone
Potent antitumor compound
  AG-CN2-0004-M010
AG-CN2-0004-M050
  10 mg
50 mg
BULK available!
Pellitorine
Tingling-inducing agent
  AG-CN2-0009-M001
AG-CN2-0009-M005
  1 mg
5 mg
BULK available!
SMI-4a
Selective inhibitor of Pim-1 & Pim-2 protein kinases
  AG-CR1-3503-M005   5 mg
BULK available!
CHS-828
Potent antitumor compound
  AG-CR1-0064-M005
AG-CR1-0064-M025
  5 mg
25 mg
BULK available!

Download our New Biochemicals Catalog with
over 100 Innovative Small Molecules

For Ordering please visit: www.adipogen.com
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