eTOPIX_New IL-36gamma ELISA Kit, Periostin, Progranulin and IL-37 Inflammatory Disease Biomarker Assays

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eTOPIX

IL-36γ - Specific Psoriasis Biomarker

New IL-36γ (human) ELISA Kit 

and other Assays to Study Inflammatory/Allergy Diseases

  • IL-36α, β, γ are members of the IL-1 family with proinflammatory effects and involvement in first-line defence against microorganisms 
  • IL-36γ is associated with skin, lung and bowel inflammation
  • IL-36γ is a specific Biomarker for Psoriasis


LIT: A.M. D'Erme, et al.; J. Invest. Dermatol. 135, 1025 (2015) | A. Balato, et al.; J. Invest. Dermatol. 136, 1520 (2016)



 
 


NEW IL-36γ (human) ELISA Kit
 
IL-36γ (human) ELISA Kit AG-45B-0008


Specifications for AG-45B-0008 

Highly specific for human IL-36γ. Detects natural & recombinant human IL-36γ. Does not cross-react with human IL-36α and IL-36β.

Sensitivity: 3pg/ml
Range: 3.9 to 250pg/ml
Sample: Serum, Cell Culture Supernatant




> Manual IL-36gamma (human) ELISA Kit

IL-36gamma (human) ELISA Kit
Discover & More



Periostin -
Reliable Biomarker for Allergic Inflammatory Diseases

 

The extracellular matrix protein Periostin is involved in various pathological processes, such as chronic inflammation, fibrosis, atherosclerosis, tumorigenesis and metastasis. Periostin is used a diagnostic marker for different diseases, related to cancer, cardio, skin and respiratory system and has become a key biomarker of "Th2-high" asthma compared to "Th2-low" asthma phenotype and a predictor of response to therapeutic agents. 

REVIEWS: Using Periostin as a Biomarker in the Treatment of Asthma: K. Izuhara, et al.; Allergy Asthma Immunol. Res. 8, 491 (2016) | Periostin: The bone and beyond: L. Idolazzi, et al.; Eur. J. Intern. Med. (Epub ahead of print) (2016)

 
Periostin (human) ELISA Kit AG-45B-0004
Periostin (mouse) ELISA Kit AG-45B-0005

Specifications for AG-45B-0004 

Detects natural and recombinant human periostin. Has been tested on human periostin isoforms 1 & 2.

Sensitivity: 15pg/ml
Range: 78 to 5000pg/ml
Sample: Serum, Plasma, Cell Culture Supernatant




> Manual Periostin (human) ELISA Kit
> Manual Periostin (mouse) ELISA Kit

Periostin (human) ELISA Kit
Discover More



Progranulin - 
Biomarker for Neurodegenerative Diseases / FTLD


Progranulin (PGRN) is a cysteine-rich secreted protein, expressed in epithelial cells, immune cells, neurons and adipocytes that shows multifunctional biological activities, including major roles in cancer, inflammation, autoimmune diseases, metabolic disease and neurodegeneration, especially used as a valuable biomarker for Frontotemporal Lobar Degeneration (FTLD). 

REVIEWS: The Role of PGRN in Alzheimer's Disease: H. Jing, et al.; Mol. Neurobiol. 53, 4189 (2016) | Progranulin: A key player in autoimmune diseases: J. Jian, et al.; Cytokine (Epub ahead of print) (2016)

 
Progranulin (human) ELISA Kit - THE STANDARD AG-45A-0018Y
Progranulin (mouse) ELISA Kit - THE STANDARD AG-45A-0019Y
Progranulin (rat) ELISA Kit AG-45A-0043Y

Specifications for AG-45A-0018Y 

Detects natural and recombinant human progranulin.

Sensitivity: 32pg/ml
Range: 63 to 4000pg/ml
Sample: Serum, Plasma, Urine, Culture Supernatant



> Manual Progranulin (human) ELISA Kit
> Manual Progranulin (mouse) ELISA Kit
> Manual Progranulin (rat) ELISA Kit

Progranulin (human) ELISA Kit
Discover More



IL-37 - New Anti-inflammatory IL-1 Family Member
 

The IL-1 family member IL-37 acts an anti-inflammatory cytokine with regulatory functions in diseases such as asthma, intestinal inflammation, SLE pathogenesis, skin inflammation and insulin resistance in obese patients. 

REVIEWS: The Role of IL-37 in Non-Cancerous Diseases: V.A Ding, et al.; Pathol. Oncol. Res. (Epub ahead of print) (2016) | Role of Anti-inflammatory Cytokines IL-35 and IL-37 in Asthma: D. Hu; Inflammation (Epub ahead of print) (2016) | A protective role of IL-37 in cancer: a new hope for cancer patients: A. Abulkhir, et al.; J. Leukoc. Biol. (Epub ahead of print) (2016)

 
IL-37 (human) ELISA Kit AG-45A-0041Y

Specifications for AG-45A-0041Y 

Detects natural and recombinant human IL-37.

Sensitivity: 10pg/ml
Range: 16 to 1000pg/ml
Sample: Serum, Plasma



> Manual IL-37 (human) ELISA Kit

 

IL-37 (human) ELISA Kit
Discover More

 
Key Research Areas:
INFLAMMASOMES | INFLAMMATION
CANCER | OBESITY & DIABETES 
IMMUNITY | STEM CELL BIOLOGY
IMMUNO-ONCOLOGY
   Product Groups:
    ELISA KITS | ANTIBODIES
    PROTEINS | SMALL MOLECULES
    FLUORESCENT DYES & PROBES

 
 
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